• Unique TIRF Functions - Unique TIRF functions like an intelligent compensation of the penetration depth shift with wavelength change during multicolour experiments, fully automated alignment and the selection of the evanescent field direction help to get highest TIRF image quality and reliable experiment data.
• Dynamic Scanner - The dynamic scanner precisely positions the laser beam and determines the exact penetration depth of the evanescent field.
• Less Training Time - Powerful Leica AF7000 fluorescence software offers full control of the TIRF system including alignment and all microscope functions – less training time and more time spent on science.
• Advanced Fluorescence Workstation - TIRF is fully integrated as an option with Leica Microsystems’ advanced fluorescence workstation - in multi-user laboratories the system meets a variety of imaging needs.
• High Image Quality - Combines TIRF and fast FRET analysis for applications such as cell membrane or single molecule analysis; vesicle tracking; fluorescence, live cell or time-lapse imaging; and more – high image quality improves scientific results.

The unique Leica AM6000 inverted micromanipulation microscope is the successor of Leica AS TP – the first and unique system ever to combine the electronic components of microscope and manipulators in one control element.

The Leica AM6000 inverted micromanipulation microscope is based on the Leica DMI6000 B inverted microscope, a fully automated research microscope and a special advanced Leica edition of Eppendorf NK2 micromanipulators.

Microscope and manipulator functions can be operated via one control panel. The system allows to automate the typical workflow of micromanipulation. It speeds up the workflow and allows easy and convenient operation. It enhances operating safety and reduce vibration.