Overview

The Leica Angle Two™ is the most technologically advanced animal stereotaxic instrument commercially available. This model includes the mouse atlas and mouse head holder. Other species can be added. The superior features of the Angle Two™ are both cost and time effective. Risk of human error is greatly reduced. The neuroscientist can improve the rigor and interpretability of stereotaxic research without adding heavy calculations or risk of error to the protocol, and using fewer animals.

The Leica Angle Two™ Stereotaxic Instrument makes it practical to do every surgery from a different approach angle without loss of accuracy or time. This enables the researcher to avoid the confound that occurs when every surgery follows the same path to the target. Accuracy and time saving features include Virtual Skull Flat™ (no trial and error, the instrument corrects exactly for deviation from skull flat orientation), and atlas integration. The instrument is fully integrated with a mouse, rat and/or hamster atlas, via a computer monitor. Scroll the atlas plates, and click on the desired target, or manually enter your target coordinates. Touch at Bregma and click, and the instrument will show you how far to move along each linear axis to reach that desired target, correcting for tilt and rotation of the manipulator. Touch Lambda, and it will show you how to reach the target given head tilt, and tilt and rotation of the manipulator. A marker will show you the path through brain of the probe tip.

The Angle Two™ allows the researcher to perform the following:

• View and select target from atlas
• Perform angled surgeries from any tilt or rotation without calculations
• Correct for head tilt
• Store target coordinates in an icon
• Continuously monitor progression of the probe through coronal plates of the atlas

Key Features