Sutter Instrument XenoWorks™ Micromanipulator

The XenoWorks Micromanipulator has been designed around our hugely-successful MP-285 electrophysiology micromanipulator, with the addition of a smooth-moving adjustable inverted joystick. Because the motor drive is based on an electrophysiology design, the XenoWorks Micromanipulator is extremely stable and resistant to ambient vibration. This stability also makes this manipulator an ideal platform for use in conjunction with the PrimeTech PMM-150FU piezo impact drive for applications such as mouse nuclear transfer and intracytoplasmic sperm injection.

Sutter Instrument MP-265/MPC-365

Our new Sutter Instrument MP-265/M "narrow format" mechanical is designed especially for patch-slice manipulator systems that require more than 2 or 3 pipettes. Coupled with our multi-manipulator controller, Sutter Instrument MPC-200, users have the ability to easily build up multi-manipulator MPC-365 systems for positioning multiple recording and stimulating pipettes.

The Sutter Instrument MP265/M mechanical builds on our existing manipulator line in several ways. First, narrow format means more manipulators can be grouped around a recording chamber. A long throw (25 mm) radial X-axis provides an easier approach to and from the optical center. Finally, travel in the Y-axis is shortened (12.5 mm) to economize on width, which is made possible because radially oriented manipulators do not require long travel in this axis.

Sutter Instrument MPC-200/MPC-325/MPC-385

Neurobiological experiments are becoming more complex. Many require multiple manipulators with control units that quickly become space and/or cost prohibitive. The Sutter Instrument MPC-200 is the solution you have been asking for. A single controller capable of running 2 manipulators! Sutter Instrument has taken the simplicity of the MP-225 controller and expanded it to run two manipulators from a single controller/ROE. The Sutter Instrument MPC-200 works with one or two of our world-renowned mechanicals, the Sutter Instrument MP-285 (MPC-385), the Sutter Instrument MP-225 (MPC-325) or the narrow format Sutter Instrument MP-265 (MPC-365). The controller is self-detecting so there is no need for manual configuration of the components.

Sutter Instrument MP-285

The flagship in our line of precision micromanipulators, the motorized Sutter Instrument MP-285 is affordable yet offers advanced features found in manipulators costing thousands more. Custom engineered stepping motors, precision cross-roller bearing slides and proprietary worm gear capstan drives form the basis of the watch-like mechanical system. The Sutter Instrument MP-285 controller provides power to the stage motors with a quiet linear power supply to minimize electrical noise radiation in your setup. Pipette holders and headstages are securely mounted to the Sutter Instrument MP-285 with one of our several unique and rigid mounting systems.

Sutter Instrument MP-225

The Sutter Instrument MP-225 is one of the newer members in the Sutter Instrument micromanipulator line. Production and design changes have allowed us to produce a motorized manipulator that is a more affordable alternative to the industry standard Sutter Instrument MP-285. While the Sutter Instrument MP-225 feature set is less comprehensive than the Sutter Instrument MP-285, it includes the most popular features with a user interface that is simpler to use. The mechanical design utilizes a miniature stepper motor and integral anti-backlash gear head. Pre-loaded ball bearing slides provide smooth movement throughout the 25mm of travel. The controller uses low-noise, linear-drive output circuitry identical to that found in the Sutter Instrument MP-285. The methodology for mounting pipette holders and headstages used with the Sutter Instrument MP-285 has been maintained in the Sutter Instrument MP-225 to allow for cross compatibility.

Sutter Instrument MP-85

The classic micromanipulator developed by Sir Huxley many years ago is still considered by many investigators to be the finest manual micromanipulator available. The Sutter Instrument MP-85 offers the advantage of a very large range of movement with its built-in coarse manipulator and precise submicron movement with the fine controls. Coarse positioning is achieved with a three axis manipulator mounted on top. The ultrafine positioning is accomplished with the large micrometers mounted on the base. These micrometers provide smooth, precise movement through a 10:1 reduction mechanism.

Sutter Instrument MM-33/MM-33A

Used in complex experiments in conjunction with our other micromanipulators, or as a stand alone unit in a teaching environment, the Sutter Instrument MM-33 is available separately for those wishing a small, practical instrument in applications not requiring submicron accuracy.

The Sutter Instrument MM-33 is the right choice for tight environments which require maximum versatility within a small space. The optional rotating base and tiltable X-axis provide even further flexibility.

Sutter Instrument MM-1 & MM-3

The Sutter Instrument MM-1 & MM-3 micropositioners are precision instruments designed to eliminate many research and design problems at a justifiable cost, especially in the case of space limitations. The Sutter Instrument MM-3 is roughly 1 3/4 inches (4.4cm) in height and less than 1 inch (2.5cm) in width and depth. The Sutter Instrument MM-1 is even smaller at a height of only 1 inch (2.5cm).

Sutter Instrument MT-2000/MT-2078

The Sutter Instrument MT-2000/MT-2078 is a motorized microscope translator system including multiple platforms for manipulators and specimen. Two general styles are available. In the classic design (Sutter Instrument MT-2000), an independent stand, the Sutter Instrument MT-75 is used for each manipulator and a similar stand, the Sutter Instrument MT-150 holds the tissue chamber. A new style (Sutter Instrument MT-2078) uses a single large, fixed stage, the Sutter Instrument MT-78-FS, to support multiple manipulators and the sample. The classic Sutter Instrument MT-2000 features free-standing columns that provide rock solid mounting for the tissue recording chamber and multiple micromanipulators. Many prefer this methodology as it maximizes working room for adjusting the microscope and changing pipettes. Furthermore, the independent stand design minimizes movement-related cross talk between manipulators. The Sutter Instrument MT-2078 single stage has the advantage that it is easy to add additional manipulators and other devices into the design as the manipulator/chamber support is one large platform.

Sutter Instrument MT-1000/MT-1078

The Sutter Instrument MT-1000/MT-1078 is a microscope translator, fixed-stage and manipulator platform for moving optical pathway electrophysiology. Two general styles are available. In the classic design (Sutter Instrument MT-1000), an independent stand is used for each manipulator and a similar stand holds the tissue chamber. A new style (Sutter Instrument MT-1078) uses a single large, fixed stage that is used for multiple manipulators and for the sample as well.

Sutter Instrument MT-70

The Sutter Instrument MT-70 and MT-71 series of stands are sturdy, stable, and extremely versatile for mounting components for a variety of research applications. They were designed for placing our heavy Huxley-style micromanipulators adjacent to any microscope. We found them to be so useful and adaptable that we also use them for mounting other items such as optical components.

Sutter Instrument MT-75

For ultimate flexibility in positioning micromanipulators or other devices adjacent to your microscope, look to the Sutter Instrument MT-75 series stands. These unique gantry systems offer adjustable vertical and horizontal axes and up to 360 degrees of rotation. Your manipulator or other device will mount to the 3/4in thick aluminum cantilever which is dovetailed for secure positioning. The cantilever assembly is mounted on a heavy 2in diameter stainless steel post. The post is supported within the same extruded aluminum tower used in the Sutter Instrument MT-70 stands. The tower can be center mounted or edge mounted to the base-plate for an additional degree of positioning freedom.Vertical positioning is achieved with an aluminum collar which securely locks onto the steel post to fix the height of the system. The Sutter Instrument MT-75 is suitable for use with most inverted microscopes, and can be adjusted from a minimum height of 8 5/8in to a maximum height of 12 1/2in. The Sutter Instrument MT-75S is suitable for most upright scopes, and can be adjusted from 6 5/8in to 9 1/2in. These systems are very stiff, deflecting approximately 2um per 25mm rise with a 1.5 kg load at the end of the cantilever.

Sutter Instrument MP-78/MPC-78

The Sutter Instrument MP-78 Large Moving Stage is available for patch slice or in vivo experiments where the microscope body cannot be moved to view different fields of view. This is most common in two-photon experiments where the excitation beam path must enter a fixed microscope. In order to visit wide-spaced fields of view, and potentially position pipettes at wide-spaced locations, the preparation and any associated manipulators must move together on a large stage.

Sutter Instrument MT-78-FS

Designed for experiments where a large single stage is dictated, the Sutter Instrument MT-78-FS large-stage platform provides solid, stable support and ample space to attach manipulators and other instruments as needed. The rigid aluminum top plate sits firmly on two of our well-known Sutter Instrument MT-75 gantry-style stands. These stands provide height adjustment and sturdy attachment to the user’s vibration table. Multiple degrees of freedom accommodate a variety of microscope and instrument arrangements.

Sutter Instrument MD-Series

For users who wish to use the Sutter Instrument MP-285 or MP-225 manipulator in conjunction with an inverted microscope, Sutter Instrument has designed a series of Microscope Dependent (MD) stands. The typical MD stand is a manipulator platform that bolts directly to the frame of an inverted microscope. Stands are available in either single-sided or double-sided versions for the most common inverted microscopes made by Nikon, Olympus, Leica, and Zeiss.